Publication of Trials Funded by the National Heart, Lung, and Blood Institute

Publication of trials funded by the National Heart, Lung, and Blood Institute.

BACKGROUND Rapid publication of clinical trials is essential in order for the findings to yield maximal benefits for public health and scientific progress. Factors affecting the speed of publication of the main results of government-funded trials have not been well characterized. METHODS We analyzed 244 extramural randomized clinical trials of cardiovascular interventions that were supported ...

Publication Speed, Reporting Metrics, and Citation Impact of Cardiovascular Trials Supported by the National Heart, Lung, and Blood Institute

BACKGROUND We previously demonstrated that cardiovascular (CV) trials funded by the National Heart, Lung, and Blood Institute (NHLBI) were more likely to be published in a timely manner and receive high raw citation counts if they focused on clinical endpoints. We did not examine the metrics of trial reports, and our citation measures were limited by failure to account for topic-related citatio...

National Heart, Lung, and Blood Institute: transitions.

I am pleased to provide an update on the policies and programs of the National Heart, Lung, and Blood Institute (NHLBI). This is an exciting time of many transitions for the federal government as a whole and the National Institutes of Health (NIH) in particular. As these changes take form, I want to assure you of our unwavering commitment to support our community of heart, lung, and blood inves...

International participation in cardiovascular randomized controlled trials sponsored by the National Heart, Lung, and Blood Institute.

OBJECTIVES The aim of this study was to describe international enrollment and participation in National Institutes of Health (NIH)-sponsored cardiovascular randomized controlled trials (RCTs). BACKGROUND RCTs provide the evidence base for major societal guidelines and profoundly influence patient care in the United States. Increased international involvement in clinical trials has been observ...

The National Heart, Lung and Blood Institute asthma program.